Message Personal Concierge Call +65 6223 8897
5.0 ★ (Google Review) · MOH HCSA Licensed · Winner Singapore SME 500 Award 2026

Longevity Screening in Singapore

Years lived in good health you can gain. Doctor-led epigenetic, microbiome, and cardiopulmonary diagnostics at Mandarin Gallery, Orchard Road.

Distinguishing healthspan—years lived free from chronic disease—from calendar lifespan through direct laboratory measurement rather than algorithm approximations.

Physician reviewing comprehensive diagnostic longevity results at Hisential Mandarin Gallery
Mandarin Gallery, Orchard Road

Private clinical suite & direct cardiopulmonary lab

SMC Doctors
MOH HCSA Licensed Licence: L/24M2064/MDS/001/242
SMC-Registered Physicians Dr. Anthony Stanislaus PBM & Dr. Julian Ng
Singapore SME 500 Award Recognised Excellence Winner 2026
Mandarin Gallery Flagship Somerset MRT Exit B · Orchard Road

Diagnostic Foundation

The Three Scientific Pillars of Longevity

Longevity medicine replaces guesswork with empirical biochemistry. We quantify cellular ageing rates, microbial ecosystem health, and cardiopulmonary capacity in direct laboratory tests.

01

Epigenetic Biological Age

Quantifies DNA methylation patterns across thousands of key genetic loci using validated epigenetic clocks to reveal your cellular age versus your calendar years.

  • Rate of biological ageing per chronological year
  • Reversible cellular senescence markers
  • Repeatable tracking at 6-to-12-month intervals
02

Gut Microbiome Sequencing

High-throughput genomic sequencing of 100 trillion microbial residents to evaluate systemic inflammation, gut barrier integrity, and metabolic synthesis.

  • Alpha & Beta bacterial diversity scoring
  • Short-chain fatty acid (SCFA) production capacity
  • LPS endotoxin markers & dysbiosis detection
03

Cardiopulmonary & Metabolic

Direct physical function testing: breath-by-breath VO2 Max gas exchange on a precision cycle ergometer and indirect calorimetry for Resting Metabolic Rate (RMR).

  • Laboratory VO2 Max and ventilatory thresholds (VT1/VT2)
  • Resting Metabolic Rate (actual basal calories/day)
  • Substrate utilization (fat vs carbohydrate oxidation)

Signature Clinical Roadmap

Interactive Longevity Tier & Healthspan Roadmap

Preview the exact biomarker scope, sample requirements, and Personal Concierge touchpoints across Hisential's four cumulative tiers before scheduling your consultation.

Cellular & Microbial Foundation

The Janus: The Baseline

Our introductory longevity programme. Establishes an objective measurement of how your cells are ageing compared to your calendar years, alongside complete genomic gut microbiome biodiversity and barrier integrity profiling.

Sample Requirements: In-clinic saliva or venous blood draw + at-home temperature-stable stool sequencing kit.
Turnaround & Analysis: 14 to 21 business days (comprehensive bioinformatics processing).
Concierge Touchpoint: Pre-consultation file collation, sample kit delivery coordination, physician review scheduling, and WhatsApp direct access.

Unhurried Clinical Pathway

1
Physician Goal-Setting

Unhurried consultation exploring family risk, lifestyle baselines & athletic targets.

2
In-Clinic & Lab Sampling

Mandarin Gallery clinic collection, home stool buffer kit, and CPET gas analysis.

3
Clinician Multi-Omic Synthesis

Dr. Julian Ng & Dr. Anthony Stanislaus interpret raw genomics into clear clinical context.

4
Action Plan & Concierge Cadence

Evidence-based prescription with repeat interval scheduling managed via WhatsApp.

Cumulative Diagnostics

Cumulative Longevity Screening Programmes

Every tier includes a doctor consultation, specimen processing, clinician interpretation, and a written action plan. Each progressive tier builds upon the one below.

Tier 1 · The Baseline

The Janus

Our starting baseline measuring how your cells and digestive ecosystem are functioning.

  • Epigenetic Biological Age (DNA methylation)
  • Gut Microbiome Sequencing (Home kit)
  • Personalised Doctor-Reviewed Action Plan
Best For: Individuals establishing their first objective cellular health baseline.

Tier 2 · The Functional

The Apollo

Everything in The Janus, plus objective metrics of physical architecture and muscular frailty.

  • All Inclusions in The Janus
  • InBody Segmental Body Composition
  • Grip Strength Dynamometer Evaluation
Best For: Patients tracking muscle quality, visceral fat, and biological frailty.

Tier 3 · The Performance

The Helios

Everything in The Apollo, plus breath-by-breath cardiopulmonary exercise testing under load.

  • All Inclusions in The Apollo
  • VO2 Max Cardiopulmonary Gas Analysis (CPET)
  • Aerobic & Anaerobic Thresholds (VT1/VT2)
Best For: Active individuals calibrating real cardiovascular fitness and aerobic power.

Diagnostic Inclusions

Comprehensive Tier Comparison

Compare diagnostic inclusions across all four cumulative tiers at a glance.

Diagnostic Investigation The Janus The Apollo The Helios The Orion ★
Doctor Consultation & Medical History ✓ ✓ ✓ ✓
Epigenetic Biological Age (DNA Methylation) ✓ ✓ ✓ ✓
Gut Microbiome Genomic Sequencing ✓ ✓ ✓ ✓
InBody Segmental Body Composition — ✓ ✓ ✓
Grip Strength Dynamometer Testing — ✓ ✓ ✓
VO2 Max Breath-by-Breath Cycle Ergometry — — ✓ ✓
Ventilatory Thresholds (VT1 & VT2) — — ✓ ✓
Resting Metabolic Rate (Indirect Calorimetry) — — — ✓
Dedicated Personal Concierge WhatsApp Support ✓ ✓ ✓ ✓

Looking to integrate comprehensive blood biochemistry or radiological imaging? Explore Add-on Packages: The Bernini (82 biomarkers) and The Da Vinci (Ultrasounds + BMD)

The Experience

What to Expect: The Four-Step Clinical Pathway

An unhurried, discreet healthcare journey designed around patient dignity, zero waiting rooms, and thorough doctor oversight.

Step 01

Physician Goal-Setting

An unhurried consultation with Dr. Julian Ng or Dr. Anthony Stanislaus at Mandarin Gallery. We explore family cardiovascular risk, baseline fatigue, digestive issues, and athletic aspirations.

Step 02

Sample Collection

In-clinic blood and saliva sampling. You receive a temperature-stable home gut microbiome kit with clear instructions. For Helios and Orion tiers, a separate cycle ergometer appointment is scheduled.

Step 03

Clinician Interpretation

Our physicians synthesize genomic sequencing, DNA methylation age, and metabolic outputs into a unified, clinically coherent narrative, eliminating conflicting data points.

Step 04

Action Plan Review

A private debrief detailing evidence-based interventions: nutrition adjustments, targeted supplementation, or training zones. Your Personal Concierge schedules reminders and repeat testing intervals.

Clinical Governance

Doctor-Led Care & Clinical Governance

Longevity medicine requires rigorous medical oversight. Our practice is directed by senior SMC-registered doctors with advanced qualifications in clinical microbiology and executive medical administration.

Dr. Julian Ng, Medical Director of Hisential Singapore
SMC Reg: M15423G

Dr. Julian Ng

Medical Director & Senior Physician

MBBS (University of Sydney, Australia)
Master of Science in Microbiology (National University of Singapore)
Certificate in Men's Health (Society of Men's Health Singapore)

Dr. Ng brings extensive postgraduate microbiological expertise to Hisential, ensuring that gut microbiome sequencing and systemic inflammatory markers are translated into rigorous, evidence-based clinical protocols.

Dr. Anthony Stanislaus PBM, Founder & Resident Physician
SMC Reg: M18515I · Public Service Medal (PBM)

Dr. Anthony Stanislaus PBM

Founder & Resident Physician

MBBS (University of Queensland), BMedSc Hons
Graduate Diploma in Family Medicine (NUS)
Executive MBA (NUS / Saïd Business School, Oxford)
Recipient of the Pingat Bakti Masyarakat (Public Service Medal)

With over 14 years of executive healthcare leadership—former Chief Operating Officer of Innoquest Diagnostics and 3-year diagnostic radiology residency at TTSH—Dr. Stanislaus champions uncompromising clinical standards and patient advocacy.

High-Touch Care

The Personal Health Concierge Model

Medical screening often suffers from disjointed administration and impersonal waiting rooms. At Hisential, every longevity patient is paired with a dedicated single human point of contact.

Zero Waiting Rooms

Appointments are scheduled with generous buffer times so you walk straight into your private consultation suite.

Direct WhatsApp Triage

Communicate directly with your coordinator for appointment alterations, pre-test preparation, and report queries.

Complete Physician Pre-Briefing

Your concierge briefs attending doctors ahead of time so you never have to repeat your health history.

Discreet, private consultation lounge at Hisential Mandarin Gallery

Clinical Self-Assessment

Longevity Readiness Assessment

Select the clinical questions that match your current priorities to receive an instant, doctor-calibrated tier recommendation.

Select all statements that apply to your current health objectives:
Assessment Recommendation 0 of 8 criteria selected

Select one or more statements above to receive a tailored diagnostic screening recommendation.

Real Feedback

Verified Patient Experiences

Authentic, unedited feedback from Google Reviews reflecting our couple-friendly, unhurried clinical environment.

★★★★★
“this clinic really caught me by surprise. I can see why their marketing is focus on men but when my partner brought me here for a health screening I found out they do screenings for all genders. This is probably the best health screening experience I’ve had, took me 2 hours to get a very comprehensive work up, didn’t feel like a factory and their customer service and patient experience is probably the best I’ve had in Singapore. Would highly recommend couples to visit this clinic.”
Teo Zixin
Google review · Verified Patient

Direct Answers

Frequently Asked Questions

Clear, doctor-reviewed explanations regarding asymptomatic testing, genome policy, and insurance reimbursement.

Quick Answer

Why screen for longevity when you feel completely fine? Most age-related biological decay occurs silently for decades before physical symptoms arise. Longevity screening measures epigenetic age acceleration, microbial dysbiosis, and cardiopulmonary efficiency so evidence-based medical and nutritional adjustments can be initiated during the reversible, pre-symptomatic window.

Why screen for longevity if I feel fine?

Most biological change happens quietly for years before symptoms appear. Longevity screening measures what is happening now, so modifiable findings such as an accelerated biological age, a dysbiotic gut or poor cardiorespiratory fitness can be addressed while there is still room to act.

What does longevity screening at Hisential actually measure?

Three layers: Epigenetics gives your biological age from DNA methylation. Gut microbiome analysis reads the microbial ecosystem shaping digestion, immunity, and inflammation. Physical function testing, including VO2 max and resting metabolic rate on a cycle ergometer, measures how your body performs today under metabolic load.

How are the four tiers structured?

The Janus, Apollo, Helios, and Orion tiers are cumulative. Each one includes everything in the tier below it and adds a further layer of measurement, so you can start at the level that fits your goals and step up later.

Do you offer whole genome sequencing?

No. Genome sequencing is not part of the Singapore longevity programme. Our screening deliberately focuses on dynamic measures that change over time and respond to treatment: epigenetics, the gut microbiome, and physical function.

Is biological age testing reliable?

The epigenetic clocks we use are peer-reviewed and clinically validated. A single reading is a snapshot, so the number is most useful as something you track. We recommend a baseline plus a repeat reading 6 to 12 months later to separate real change from measurement variation.

Can the results predict when I will get sick?

No, and we are honest about this. These are measurements, not deterministic verdicts. Their clinical value lies in what they empower you and your doctor to adjust next, not in forecasting disease.

How often should each measure be repeated?

Epigenetic age should be re-evaluated every 6 to 12 months while you are actively making lifestyle changes. Gut microbiome sequencing every 3 to 6 months while changing diet or treating dysbiosis, otherwise annually. VO2 max and resting metabolic rate every 3 to 6 months during a structured training block.

Is the gut microbiome kit easy to use at home?

Yes. The kit contains everything you need with simple written instructions. Collection takes only a few minutes, and the preservation buffer ensures the sample is shelf-stable for several days at room temperature before clinic drop-off or courier collection.

How long do results take?

It depends on the laboratory handling each sample. VO2 Max and RMR data are available immediately. Genomic sequencing and DNA methylation take approximately 14 to 21 business days. Your Personal Health Concierge confirms the reporting timeline when your samples are collected and tracks every sample until your action-plan session is booked.

Will I need additional tests afterwards?

Sometimes. If an atypical result warrants secondary confirmation, your doctor will recommend the next clinical step. Anything outside your selected tier is quoted transparently before any arrangement is finalized.

Can I use MediSave or insurance at Hisential?

Fees are private and payable in full at the visit. MediSave, CHAS, and Healthier SG subsidies do not apply. Some private insurance plans cover specialist investigations on a reimbursement basis: you pay the clinic and claim back from your insurer afterwards. The concierge provides all necessary itemised documentation and assists with claim paperwork. 0% interest-free instalment payment plans are available upon request.

Can I share my results with my own doctor?

Yes. The full written report is yours. We can also coordinate directly with another physician or specialist on your behalf if you prefer.

Find Our Clinic

Mandarin Gallery Flagship & Hours

Discreet private practice located along Orchard Road, easily accessible via Somerset MRT Station.

Flagship Address

333A Orchard Road, #04-13 Mandarin Gallery, Singapore 238897

Steps from Somerset MRT Station (NS23 Exit B, ~2 mins walk). Mandarin Gallery underground car park with validation.

Operating Hours

Monday – Friday: 10:00 AM – 7:00 PM
Saturday – Sunday: 10:00 AM – 2:00 PM (Weekends by appointment)

Direct Contact

Phone: +65 6223 8897 / +65 3125 6028
WhatsApp Concierge: +65 8963 5233
Email: orchard.clinic@hisential.com

Begin Your Healthspan Journey

Measure How You Are Ageing, Done Properly.

Doctor-led consultations start from S$50 after GST. Speak with our Personal Health Concierge on WhatsApp to sequence your testing itinerary at Mandarin Gallery.

WhatsApp Concierge